The European Society of Cardiology (ESC) has released updated guidelines for managing peripheral arterial and aortic diseases (PAAD), emphasizing a comprehensive approach that acknowledges these conditions as part of the same cardiovascular system. The guidelines, aimed at cardiologists, highlight the importance of screening for PAAD, particularly in individuals with cardiovascular risk factors, family history, or syndromic features. The guidelines advocate for a multidisciplinary approach to treatment, including lifestyle modifications, optimal pharmacological therapy, and interventional procedures when necessary. The importance of ongoing follow-up by vascular specialists and cardiologists is emphasized, especially for women who may present with atypical symptoms. The new guidelines aim to improve patient outcomes by ensuring consistent and coordinated care for PAAD, a chronic condition affecting millions worldwide.